Tell me about a time you disagreed with your product manager about direction.
Whether you operate as a peer in the trio or defer by default. They want evidence you can disagree with substance (research, data, a prototype) rather than taste, and that you can commit cleanly when the call goes against you.
Pick a disagreement about what to build or for whom, not a visual nitpick. Describe the evidence you brought: user sessions, funnel data, or a quick prototype that made the argument concrete instead of rhetorical. Cover how the decision actually got made and what happened after. If you lost the argument, say so and describe how you committed; panels trust that story more than an undefeated record.